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20-(tert-Butoxy)-20-oxoicosanoic acid
CAS No. 683239-16-9
20-(tert-Butoxy)-20-oxoicosanoic acid ( —— )
产品货号. M28903 CAS No. 683239-16-9
20-(叔丁氧基)-20-氧代二十烷酸是一种基于烷基链的 PROTAC 连接剂。 20-(叔丁氧基)-20-氧代二十烷酸是一种不可裂解的 ADC 连接体，用于合成抗体药物偶联物 (ADC)。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 500MG | ￥405 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称20-(tert-Butoxy)-20-oxoicosanoic acid
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述20-(叔丁氧基)-20-氧代二十烷酸是一种基于烷基链的 PROTAC 连接剂。 20-(叔丁氧基)-20-氧代二十烷酸是一种不可裂解的 ADC 连接体，用于合成抗体药物偶联物 (ADC)。
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产品描述20-(tert-Butoxy)-20-oxoicosanoic acid is a alkyl-chain-based PROTAC linker. 20-(tert-Butoxy)-20-oxoicosanoic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
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体外实验ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体GABA Receptor
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研究领域——
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适应症——
化学信息
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CAS Number683239-16-9
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分子量398.628
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分子式C24H46O4
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纯度>98% (HPLC)
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溶解度——
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SMILESCC(C)(C)OC(=O)CCCCCCCCCCCCCCCCCCC(O)=O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Manev H, et al. Progabide, a GABA mimetic drug, stimulates the secretion of plasma corticosterone in rats. Pharmacol Biochem Behav. 1987 Dec;28(4):443-6.
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